[PN Booster for Eyes] Endranhiller EYE

Features of EYE ENDRAN

• Recently, with the expiration of patents, various PN skin booster products have been launched. EYE ENDRAN shows similarities to the existing ReXran Original in terms of PN content and efficacy, and similarly uses PN ingredients extracted from salmon. Since it is cost-effective, it may be suitable for those considering consistent care. PN derived from trout or other fish may differ from PN extracted from salmon, so it is important to check the source of the raw material.
• The procedure is possible not only under the eyes but also on sensitive areas such as the eyelids or the outer corners of the eyes. We delicately adjust the injection depth according to the desired location to perform a customized micro-papule treatment.
• The PN ingredient is injected as a full 2cc dose without dilution with saline solution.
• The product's low viscosity helps minimize pain during the procedure. The micro-papules also subside relatively quickly.
• Developed specifically for the eye area, it can be safely administered to sensitive areas around the eyes.
• Compared to general PN products, the pain burden is relatively low, making full-face treatment possible. It can help improve facial dullness, inner dryness, and fine wrinkles.
• The clinic's medical staff are skilled in pharmacopuncture and injection procedures. This allows for precise injection of PN ingredients into the dermal layer, and after the procedure, the micro-papules around the eyes are personally checked with the patient.

What is EYE ENDRAN (PN) Skin Booster?

EYE ENDRAN is a skin booster with PN (Polynucleotide) ingredients specially designed for the delicate skin around the eyes.

It is a procedure that can help improve various concerns such as fine wrinkles, dark circles, and inner dryness around the eyes.

It has similar PN ingredients and content to the existing ReXran Healer but is specially formulated for thin skin, like that around the eyes. This provides a smoother sensation during injection, reduces pain, and lessens the burden of micro-papule formation.

Why consider EYE ENDRAN for the eye area?

The skin around the eyes is particularly thin and sensitive compared to other areas of the face.

Such thin skin reacts easily to external stimuli, and changes due to aging or dryness can appear relatively quickly.

As this area is prone to a weakened skin barrier, it's common for several issues such as inner dryness, fine wrinkles, and bluish dark circles to appear simultaneously.

However, the eye area has structural characteristics of less subcutaneous fat and a thin dermal layer. Therefore, general moisturizers or eye creams alone may feel insufficient.

This is also why precisely injecting PN ingredients into the dermal layer to promote skin regeneration can help improve the eye area.

What is PN (Polynucleotide)?

PN is a high-purity, biocompatible substance extracted from salmon DNA.

Compared to the commonly known PDRN, PN has a relatively larger molecular weight and may have superior persistence in the skin and a greater ability to induce a response in the dermal layer.

While PDRN aids in basic skin hydration and regeneration, PN can be understood as directly stimulating the dermal layer to contribute to the improvement of skin structure.

PN can help improve skin through various processes.

It stimulates fibroblasts to help produce collagen and elastin. This can contribute to giving elasticity to the skin, alleviating fine wrinkles, and making the skin surface healthier.

It can increase the secretion of growth factors such as TGF, FGF, and VEGF, promoting skin recovery and aiding in the regeneration of damaged tissue. Additionally, it can help alleviate inflammatory responses and maintain healthy skin.

It induces epidermal cell regeneration and strengthens the skin barrier. This can enhance the binding power between keratinocytes, preventing moisture loss and helping improve inner dryness.

The skin has a barrier structure where keratinocytes can be compared to bricks and intercellular lipids to cement.

PN helps in this cement-like role and restores it, inhibiting moisture evaporation. This can contribute to improving inner dryness and sensitivity.

It can help restore damaged dermal tissue and increase its thickness. This can reinforce thinned dermis, contributing to the alleviation of dark circles and improvement of fine wrinkles.

The skin has a barrier system composed of keratinocytes and intercellular lipids. PN helps reduce skin moisture loss by enhancing the function of these intercellular lipids. As a result, improvement in inner dryness and skin sensitivity can be expected.

Meaning of Micro-papules and Dermal Layer Injection

Due to its structure, the dermal layer has a relatively narrow internal space.

When the medication is injected during the procedure, the skin may temporarily swell.

This is called the micro-papule phenomenon, which can be seen as an indicator that the medication has reached the target dermal layer.

After the procedure, the medical staff will check the micro-papules with the patient and provide an explanation.

With general PN products, micro-papules often persist for several days. However, EYE ENDRAN has low viscosity, so most are absorbed quickly within 1 week. Furthermore, the pain burden is relatively low, making it comfortable to consider for sensitive areas like the eye area.

Recommended for those who:

• Are concerned about fine wrinkles beginning to appear around the eyes.
• May also be suitable for those concerned about bluish dark circles. The bluish appearance around the eyes is due to the relatively thin dermis allowing blood vessels to show through. EYE ENDRAN can subtly reinforce the thickness of the dermis, contributing to the improvement of dark circles.
• Experience makeup not applying well and rough skin texture due to inner dryness.
• Some people hesitate about lifting procedures because their skin is sensitive and thin.
• Sometimes, it's difficult to feel sufficient improvement with eye cream alone.
• Even if you have fine wrinkles around your eyelids but were told the procedure would be difficult, this treatment can be considered.
• This treatment is for those who are concerned about fine wrinkles around their eyes and wish to improve them.

Treatment Cycle and Duration of Effects

• Typically, we recommend a total of three treatments, spaced one month apart.
• Afterward, touch-up treatments every 6 months help maintain the effects.
• Generally, the treatment effects can last from 6 months to 1 year, though individual results may vary.
• The pain during the procedure is relatively mild, and any embossing marks that appear after treatment usually subside naturally within 1 to 3 days.

A Message from Our Head Doctor

Eye area treatments go beyond simply smoothing wrinkles; they focus on activating the skin's natural regenerative and restorative abilities.

Through the 'Eye Endran' treatment, you can expect changes deep within the skin that are difficult to achieve with topical eye creams alone.

Sometimes, skin concerns arise that are difficult to improve with topical skincare products and routines alone.

In such cases, an approach that replenishes the skin from within is needed, and a procedure that increases the thickness of the dermal layer can be one solution.

The 'Eye Endran' treatment can be considered as a starting point for such internal skin improvement.

A genuine commitment to skin improvement translates into the delicate and precise touch of the practitioner.

Accurate drug injection, thorough post-procedure checks, and thoughtful consideration for patient satisfaction are all part of this process.

Our medical team will meticulously oversee and accompany you through every step of this journey.